Lamotrigine
| Lamotrigine | |
|---|---|
 | |
| Molecule | C9H7CI2N5 |
| Compound | Lamotrigine |
| Era | Modern |
| Origin | UK |
| Archetype | Acidhouse |
| Ancestor | Irish Druids |
| Swag Score | 1 |
| Date Added | 2025-01-12 |
[view source]Effects & Properties
Effects: Lamotrigine is an anticonvulsant and mood-stabilizing medication primarily used to treat epilepsy (to control seizures) and bipolar disorder (to prevent mood swings, particularly depressive episodes). Common side effects include dehydration, dizziness, headache, nausea, and in some cases skin rashes.
Natural Occurrence: Lamotrigine does not occur naturally and is purely a synthetic compound.
[view source]History
Lamotrigine was developed by GlaxoSmithKline's precursor Wellcome Research Laboratories in the UK during the 1980s, initially as an anticonvulsant for epilepsy. It received FDA approval in the United States in 1994 for epilepsy treatment and was subsequently approved for bipolar disorder maintenance therapy in 2003. Its relatively mild side effect profile compared to older mood stabilizers like lithium has made it one of the most widely prescribed psychiatric medications worldwide.
[view source]Connections
Archetype: Acidhouse
Ancestor: Irish Druids
Tarot Card: Justice
PubChem: Lamotrigine
Paired With: Lithium
[view source]Sources
- https://pubchem.ncbi.nlm.nih.gov/compound/Lamotrigine
- https://www.drugs.com/monograph/lamotrigine.html
- https://medlineplus.gov/druginfo/meds/a695007.html
- Lamotrigine - Wikipedia
- Lamotrigine - StatPearls (NCBI)
- Drug Approval Package: Lamictal NDA 2003 - FDA
- Lamotrigine in the maintenance treatment of bipolar disorder (PMC)